New systems are improving health care delivery for women concerned about breast cancer and breast related diseases. Join us for an overview of new developments including MRI as a diagnostic tool, genetic testing, new reconstruction procedures, and current and upcoming clinical trials related to breast disease. Series: “Women’s Health Today” [8/2006] [Health and Medicine] [Professional Medical Education] [Show ID: 11115]
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Breast cancer is no longer a killer. Learn what breast cancer is, how it is diagnosed, how to do a breast self exam and what happens during a mammogram. Topics covered are stages and survival rates of breast cancer, reducing your risk of breast cancer, genetic risks, environmental and lifestyle risks, diet and breast cancer, chemotherapy, radiation, surgery and reconstruction.
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The Link Between Genetics And Colon Cancer
Genetic drift , selection , migration, etc., are parameters which are used to construct models that allow us to generate predictions and obtain deeper insight.
The discovery of DNA and the elucidation of the biophysical substrate which constrains the modes of inheritance in a concrete manner opened up the startling vistas of molecular evolutionary genetics. Generally, gene mutations can disrupt an entire protein, but in colon cancers, only half the APC protein is lost, while the other half remains, Ahmed explains. Her work in fruit flies suggests a reason for this unexplained phenomenon.
Genes, such as Notch 3, were affected by the stage of tumorigenesis. After pathway analyses, many genes were identified that were over-represented for their respective biological processes (genes involved in the metabolism of carbohydrates and lipids, ion transport and signaling pathways).
Colon cancer is very rare in people under 30 years of age. Most people diagnosed with the disease are in their 50?s or 60?s. Colon cancer is one of the most common forms of cancer in the United States for both men and women. Also referred to as colorectal cancer, colon cancer occurs in the large intestine (colon) or the rectum (end of the colon).
Colon cancer is the second-leading cause of cancer deaths. The best way to detect colon cancer is with a colonoscopy, a screening exam that involves inserting a flexible, lighted tube through the rectum up to the colon and viewing images on a monitor.
Colon cancer is often fatal if the cancer cells have spread unchecked through the lymphatic system or bloodstream to adjacent and/or distant tissues. Colorectal cancer has a strong tendency to metastasize to the liver, which represents the leading cause of death for people with the disease.
Colon cancer is preventable. The most important step towards preventing colon cancer is getting a screening test. Colon cancer is caused by the abnormal growth of cells in the lining of the bowel. Usually small lumps called polyps begin to form.
Generally, the less the olive oil is handled, the closer to its natural state and the better it is. Generally, the deeper a tumor has penetrated the bowel wall, the more difficult it is to cure with surgery alone. Generally, digestive diseases have been considered by psychiatry to result from anger turned inward.
It is now known that normal people’s immune systems are able to recognize and destroy tiny cancer cells before they can spread. In the diseased or depressed person, the immune system does not function efficiently and may allow cancer to start.
Screening works because colon cancer is usually a slow-growing disease that starts with adenomatous polyps, small, protuberant growths inside the colon that may contain precancerous cells.
Screening tests are designed to find these polyps so doctors can remove them before they become cancerous. Screening saves lives.”.Here are some myths about colon cancer and the facts patients need to know. Myth: Colon cancer only affects men Colon cancer affects both men and women, in fact approximately 26,000 women die every year from colon cancer.
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Question by Lyssa: Genetic disease is basically metabolic disorder?
Question: Genetic disease is basically metabolic disorder. Explain what this statement means. Give one example to help.
My professor asked this question on one of our exams. It had me really confused. Can someone please explain?
Thanks!
Best answer:
Answer by scottsdalehigh64
This statement is not true. Yes, there are genetic diseases that are metabolic disorders, such as phenylketonuria. However, there are others that I would not consider to be a metabolic disease, such as sickle cell disease. The question depends on how broadly one defines the idea of metabolism. I don’t use the term metabolic for everything that is biochemical.
One other point is that genetic disorders in the somatic cell line (the vast majority of cells that make up the body but do not provide DNA to fertilize the next generation of offspring) can result in uncontrolled growth called cancer. I don’t regard cancer as a metabolic disorder.
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Genetic Testing Shows Promise for Prostate Cancer
Prostate cancer is still one of the leading cancers among men, and it is projected that roughly one in every six American men will be diagnosed with this type of cancer within their lifetime.
Add to that the fact that these statistics may not account for those that have not been diagnosed, and you have a full fledged “epidemic”, if you look at it from a percentage of population standpoint. In fact, many people reading this probably know someone that has been diagnosed with this cancer, or may have even had a brush with it themselves.
Aside from the fact that it is a leading cancer form in men, it also is considered in males to be a second leading cause of death. It’s no wonder that prostate cancer is at the forefront of men’s health and prevention in medical research when it comes to prevention, detection and treatment.
Researchers have been hard at work to come up with alternative testing to the still most popular form of testing, the PSA test. PSA stands for Prostate Specific Antigen, which is an enzyme that is released by this male-specific gland, which tends to be released in much higher amounts when the gland is inflamed or enlarged, or is fighting cancer.
It is a test combined with a digital rectal exam, that many men find uncomfortable for obvious reasons, and may want to naturally avoid after they reach the age of fifty years old. This is the age when doctors recommend their male patients start getting this test, since after fifty years old the risk of getting this cancer increases significantly.
The PSA test itself is actually a simple blood test, and has been criticized for sometimes being unreliable and creating false positives and false negatives, hence the search for better screening methods. The screening method that is being worked on currently is one that may be more spot-on than the current mode of detection via rectal exam combined with the PSA test.
It is the new buzzword in the scientific community for a variety of diseases and cancer in the world of detection : genetic testing. Genetic testing has proven to be a very promising method of finding cancer markers in individuals because it can be more detailed in it’s individual assessment, and finding genes responsible for cancers and other diseases is pretty much a fool proof method of detecting likelihood of cancer or actual cancer itself.
While genetic testing can definitely help either to rule out prostate cancer or to give the doctor and patient a pretty good idea if further prevention or treatment should take place, it cannot as of yet be used in and of itself as a test, but instead is a stepping stone to determining the validity of PSA screenings and digital rectal exams.
It’s basically giving a more complete answer as to whether tests that are done are actually an accurate predictor of whether a patient has it, and whether treatment should be commenced. Many doctors and patients feel that with a more complete and definitive answer in testing, they feel more comfortable with diagnosis and prevention testing, and more confident that they are getting the correct results. This renewed confidence could lead more men to take part in prevention and detection screening.
Currently the largest studies in genetic testing for prostate cancer are being carried out in Sweden, and are looking promising, but as of yet they are not conclusive and the method needs more defining and sharpening.
One thing is for sure, that genetic testing is proving to be an up and coming tool in the definitive and more accurate detection of many different kinds of cancers, including breast cancer in women. With continued research and refining, genetic testing may prove to be of great benefit for men in the prevention of prostate cancer advancement.
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